Annual Chemistry Fall Conference 2024
The SARS CoV 2 Macrodomain and how to inhibit it The nonstructural protein 3 (NSP3) macrodomain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Mac1) removes adenosine diphosphate (ADP) ribosylation posttranslational modifications, playing a key role in the immune evasion capabilities of the virus responsible for the coronavirus pandemic. Starting from a collaborative X-ray-based fragment […]